Company Details

  • Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

  •  [Hebei,China]
  • Business Type:Manufacturer , Trade Company
  • Main Mark: Americas , Asia , East Europe , Europe , North Europe , Oceania , Other Markets , West Europe , Worldwide
  • Exporter:81% - 90%
  • Certs:ISO9001, CCC, FDA, MSDS, FCC, REACH, RoHS
  • Description:Decitabine,5-aza-2-deoxycytidine,CAS No 2353-33-5
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Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

Decitabine,5-aza-2-deoxycytidine,CAS No 2353-33-5

Home > Products > APIs And Intermediates > Decitabine Intermediates > Decitabine 5-aza-2'-deoxycytidine CAS No 2353-33-5

Decitabine 5-aza-2'-deoxycytidine CAS No 2353-33-5

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    Payment Type: L/C,T/T,D/P
    Incoterm: FOB,CIF
    Min. Order: 0.01 Kilogram
    Delivery Time: 7 Days

Basic Info

Model No.: DM 2353-33-5

Function: Specialist Drugs

Certification: FDA, SGS, GMP

Grade Standard: Medicine Grade

Type: Chemical Reagent

State: Solid

Volatile: Not Volatile

Appearence: White Powder

Purity: 99%

Additional Info

Packaging: As required

Transportation: Ocean,Air

Port: Shanghai,Shenzhen,Qingdao

Product Description

Decitabine 5-aza-2'-deoxycytidine Cas 2353-33-5:

Product Name:Decitabine
Synonyms:4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-on;
5-AZA-CDR; 5-Aza-2'-deoxycytidine
CAS No:2353-33-5
Molecular Formula: C8H12N4O4
Moculer weight: 228.21
EINECS:219-089-4

Appearence: White to Off-white powder

COA: can be requested

Storage condition: keep in seal, cool and dry place

Stability: Stable. May be light or air sensitive. Incompatible with strong oxidizing agents.


Cyproterone acetate has antagonistic properties towards the 5-Aza-2'-Deoxycytidine, has been reported to cause phosphorylation inhibition of 2'-deoxycytidine in certain cells and the incorporation of 2'-deoxycytidine into DNA. Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits Dnmt (DNA methyltransferase). DNA methylation has been noted to be important in determining apoptotic susceptibility to histone deacetylase inhibitors, and its prevention can cause gene silencing and transcriptional repression. Other studies suggest that cell exposure to 5-Aza-2'-Deoxycytidine causes a change in replication timing, reactivation of repressed genes, and decondensation of heterochromatin. Furthermore, this agent demonstrates the ability to induce histone hyperacetylation in murine centromeric heterochromatin and also affect intranuclear distribution of histone deacetylase 2.

COA of Decitabine 5-aza-2'-deoxycytidine CAS 2353-33-5:

ANALYSIS

SPECIFICATION

RESULTS

Appearance

Fine powder

Complies

Odor

Characteristic

Complies

Extract Ratio

10:1

Complies

Sieve analysis

100% pass 80 mesh

Complies

Loss on Drying

≤5.0%

2.98%

Residue on Ignition

≤5.0%

2.32%

Heavy Metal

<10ppm

Complies

As

<2ppm

Complies

Residual Solvents

Eur.Pharm.

Complies

Microbiology

Total Plate Count

<1000/g

145/g

Yeast & Mold

<100/g

62/g

E.Coli

Negative

Complies

Salmonella

Negative

Complies


Our productions of Decitabine Intermediates:

Decitabine intermediates


Picture of Decitabine 5-aza-2'-deoxycytidine CAS 2353-33-5:

Decitabine 5-aza-2'-deoxycytidine


Package & Shipping:

1. Preferentially DHL or FedEx for quantity less than 50KG; Air shipping for 100KG above; Sea shipping for quantity over 500KG.
2. We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.
Delivery can be offered.
- Utilizing your own freight-forwarder
- FOB to a port in China
- CIF to a port near you

Decitabine CAS 2353-33-5


Our Service:

1. Supply high quality products with reasonable prices for pharmaceutical factory.
2. In time delivery, Packing pictures and loading video before loading.
3. Various documents(COA, MSDS, ROS, MOA etc.) and factory audit available.
4. Pre-sale consultation and post-sale service available.
5. Provide market informations to make customers fully informed.


Company Information:

Shijiazhuang Dingmin Pharmaceutical Sciences Co., Limited is a professional company ocusing on the R&D, production, marketing and technical service of APIs and Pharmaceutical Intermediates. We have a R&D center and two plants in Shijiazhuang, Hebei Province. Our Products include Active Pharmaceutical Ingredients (API), pharmaceutical and Agrochemical Intermediates and chiral compounds. We have won the trust of a wide range of customers/partners in the industry. Our major products are antineoplastic, cardiovascular and antibiotics and their intermediates.
In order to maintain continuous innovation and R & D capability, we maintain long-term and close cooperation with many research institutions and universities, Our co-production plants are located in Anhui, Jiangsu, Zhejiang and Inner Mongolia. The products have been sold to Europe, America, Southeast Asia and other countries and regions
Having upholding the " integrity, profession , innovation, win-win" as business philosophy, we believe that we are able to be stronger and stronger because of the excellent quality, favorable price and full-hearted service. We would like to sincerely welcome friends from all sectors to co-create a brilliant tomorrow together.

CAS 2353-33-5


Looking for ideal Decitabine Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the 5-aza-2-deoxycytidine are quality guaranteed. We are China Origin Factory of CAS No 2353-33-5. If you have any question, please feel free to contact us.

Product Categories : APIs And Intermediates > Decitabine Intermediates

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  • Decitabine 5-aza-2'-deoxycytidine CAS No 2353-33-5
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