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Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.
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Add: No. 52 Zhaiying South Street, Shijiazhuang, Hebei, China
E-mail: sales@dingminpharma.com

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Products

Active Pharmaceutical Ingredients (APIs)

No.ProductCAS No.
1Dantrolene Sodium24868-20-0
2Olaparib763113-22-0
3Acalabrutinib1420477-60-6
4Brigatinib1197953-54-0
5Crizotinib877399-52-5
6Eltrombopag Olamine496775-62-3
7Binimetinib606143-89-9
8Selexipag475086-01-2
9Tofacitinib Citrate540737-29-9
10Upadacitinib hemihydrate2050057-56-0
11Tasimelteon609799-22-6
12Baricitinib1187594-09-7
13Dacomitinib1110813-31-4
14Lenvatinib mesylate857890-39-2
15Erdafitinib1346242-81-6
16Sulopenem Etzadroxil1000296-70-7
17Tepotinib Hydrochloride Hydrate1946826-82-9
18Lesinurad878672-00-5
19Dabrafenib Mesylate1195768-06-9
20Capmatinib HCl hydrate1865733-40-9
21Ruxolitinib phosphate1092939-17-7
22Vandetanib443913-73-3
23Darolutamide1297538-32-9
24Gefitinib184475-35-2
25Osimertinib mesylate1421373-66-1
26Siponimod1230487-00-9
27Siponimod fumarate1234627-85-0
28Fingolimod HCl162359-56-0
29Fingolimod162359-55-9
30Tafamidis594839-88-0
31Tafamidis Meglumine951395-08-7
32Enzalutamide915087-33-1
33Lumacaftor (VX-809)936727-05-8
34Tezacaftor (VX-661)1152311-62-0
35Ivacaftor (VX-770)873054-44-5
36Elexacaftor (VX-445)2216712-66-0
37Vanzacaftor (VX-121)2374124-49-7
38Deutivacaftor (VX-561)1413431-07-8
39Rimegepant Sulfate1374024-48-2
40Diroximel Fumarate1577222-14-0
41Danuglipron2230198-02-2
42Mitotane53-19-0
43Cabozantinib Malate1140909-48-3
44Vibegron1190389-15-1
45Zavegepant HCl1414976-20-7
46Ceritinib1032900-25-6
47Fezolinetant1629229-37-3
48Elinzanetant929046-33-3
49Trametinib DMSO solvate1187431-43-1
50Vismodegib879085-55-9
51Risdiplam1825352-65-5
52Givinostat hydrochloride199657-29-9
53Givinostat hydrochloride monohydrate732302-99-7
54Avapritinib1703793-34-3
55Daraxonrasib2765081-21-6
56Lazertinib443797-96-4
57Lemborexant1369764-02-2
58Carboplatin41575-94-4
59Cisplatin15663-27-1
60Oxaliplatin63121-00-6
61Paclitaxel33069-62-4
62Docetaxel114977-28-5
63Bleomycin Sulfate9041-93-4
64Vincristine Sulphate2068-78-2
65Vinblastine Sulfate143-67-9
66Vinorelbine Tartrate125317-39-7
67Everolimus159351-69-6
68Sirolimus53123-88-9

Pharmaceutical Intermediates

Key intermediates organised by drug family. Click a name below to jump to the corresponding group.

Selexipag Enzalutamide Ivacaftor Lumacaftor Tezacaftor Siponimod Ozanimod Fingolimod Darolutamide Apalutamide Erlotinib Sorafenib Crizotinib Sunitinib Pazopanib Axitinib Lenvatinib Tofacitinib Abiraterone Venetoclax Lorlatinib Brexpiprazole Diroximel Fumarate Vericiguat Eltrombopag Vibegron Fezolinetant Vismodegib Trametinib Elinzanetant Dantrolene Sodium Tovorafenib Lazertinib Lemborexant Daraxonrasib
Selexipag & Intermediates
No.ProductCAS No.
1Selexipag475086-01-2
22-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetic acid475085-57-5
34-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol475086-75-0
45-Chloro-2,3-diphenylpyrazine41270-66-0
52-Bromo-5,6-diphenylpyrazine243472-70-0
64-(Isopropylamino)butanol42042-71-7
Enzalutamide & Intermediates
No.ProductCAS No.
14-Isothiocyanato-2-(trifluoromethyl)benzonitrile143782-23-4
2N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester1332524-01-2
3N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine1289942-66-0
Ivacaftor & Intermediates
No.ProductCAS No.
1Ivacaftor (VX-770)873054-44-5
24-oxo-1,4-dihydroquinoline-3-carboxylic acid13721-01-2
35-amino-2,4-di-tert-butylphenol hydrochloride873055-58-4
42,4-di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl methyl carbonate1246213-45-5
Lumacaftor & Intermediates
No.ProductCAS No.
1Lumacaftor (VX-809)936727-05-8
21-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile862574-87-6
31-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxylic acid862574-88-7
46-chloro-5-methylpyridin-2-amine442129-37-5
53-(6-amino-3-methylpyridin-2-yl)benzoic acid tert-butyl ester1083057-14-0
Tezacaftor & Intermediates
No.ProductCAS No.
1Tezacaftor (VX-661)1152311-62-0
22-bromo-5-fluoro-4-nitroaniline952664-69-6
3(R)-(2,2-dimethyl-1,3-dioxolan-4-yl)methanol14347-78-5
4(((2,2-dimethylbut-3-yn-1-yl)oxy)methyl)benzene1092536-54-3
52-[1-(benzyloxy)-2-methylpropan-2-yl]-6-fluoro-5-nitro-1H-indole1638771-94-4
Siponimod & Intermediates
No.ProductCAS No.
1Siponimod1230487-00-9
2Siponimod hemi-fumarate1234627-85-0
3(E)-4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzaldehyde1230487-01-0
4O-(4-cyclohexyl-3-(trifluoromethyl)benzyl)hydroxylamine800379-62-8
51-(3-ethyl-4-(hydroxymethyl)phenyl)ethan-1-one1378888-43-7
Ozanimod & Intermediates
No.ProductCAS No.
1Ozanimod1306760-87-1
2Ozanimod HCl1618636-37-5
3(R)-tert-butyl (4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate1306763-31-4
41-oxo-2,3-dihydro-1H-indene-4-carbonitrile60899-34-5
5Carbamic acid, N-[(1S)-2,3-dihydro-4-[(hydroxyamino)iminomethyl]-1H-inden-1-yl]-N-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-, 1,1-dimethylethyl ester1306763-62-1
63-cyano-4-isopropoxybenzoic acid258273-31-3
Fingolimod & Intermediates
No.ProductCAS No.
1Fingolimod162359-55-9
2Fingolimod HCl162359-56-0
3N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)acetamide249289-10-9
4N-[1,1-bis[(acetyloxy)methyl]-3-phenylpropyl]acetamide162359-95-7
52-acetamido-2-(4-octanoylphenethyl)propane-1,3-diyl diacetate249289-07-4
62-acetamido-2-(4-octylphenethyl)propane-1,3-diyl diacetate162358-09-0
Darolutamide & Intermediates
No.ProductCAS No.
1Darolutamide1297538-32-9
25-acetyl-1H-pyrazole-3-carboxylic acid1297537-45-1
3(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile1297537-41-7
42-chloro-4-(1H-pyrazol-3-yl)benzonitrile1297537-37-1
55-acetyl-1(2)H-pyrazole-3-carboxylic acid ethyl ester37622-89-2
Apalutamide & Intermediates
No.ProductCAS No.
1Apalutamide956104-40-8
25-amino-3-(trifluoromethyl)picolinonitrile573762-62-6
35-isothiocyanato-3-(trifluoromethyl)picolinonitrile951753-87-0
Erlotinib & Intermediates
No.ProductCAS No.
1Erlotinib183321-74-6
2Erlotinib HCl183319-69-9
34,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile236750-65-5
46,7-bis(2-methoxyethoxy)quinazolin-4(3H)-one179688-29-0
Sorafenib & Intermediates
No.ProductCAS No.
1Sorafenib tosylate475207-59-1
24-chloro-N-methylpyridine-2-carboxamide220000-87-3
34-chloro-3-(trifluoromethyl)phenyl isocyanate327-78-6
44-(4-aminophenoxy)-N-methylpicolinamide284462-37-9
Crizotinib & Intermediates
No.ProductCAS No.
1Crizotinib877399-52-5
21-piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester877399-73-0
3(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine877399-00-3
4tert-butyl 4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-3-yl]pyrazol-1-yl]piperidine-1-carboxylate877399-51-4
Sunitinib & Intermediates
No.ProductCAS No.
1Sunitinib malate341031-54-7
25-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid253870-02-9
3ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate2199-59-9
45-fluoro-1,3-dihydro-2H-indol-2-one56341-41-4
Pazopanib & Intermediates
No.ProductCAS No.
1Pazopanib HCl635702-64-6
22,3-dimethyl-2H-indazol-6-amine hydrochloride635702-60-2
33-amino-6-methylbenzenesulfonamide6973-09-7
Axitinib & Intermediates
No.ProductCAS No.
1Axitinib319460-85-0
22-mercapto-N-methylbenzamide20054-45-9
36-iodo-1H-indazole261953-36-0
Lenvatinib & Intermediates
No.ProductCAS No.
1Lenvatinib mesylate857890-39-2
21,4-dihydro-7-methoxy-4-oxo-6-quinolinecarbonitrile417721-15-4
34-amino-3-chlorophenol17609-80-2
Tofacitinib & Intermediates
No.ProductCAS No.
1Tofacitinib477600-75-2
2Tofacitinib citrate540737-29-9
3(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride1062580-52-2
44-chloropyrrolo[2,3-d]pyrimidine3680-69-1
5(2,5-dioxopyrrolidin-1-yl) 2-cyanoacetate56657-76-2
Abiraterone & Intermediates
No.ProductCAS No.
1Abiraterone acetate154229-18-2
2Abiraterone154229-19-3
317-iodoandrosta-5,16-dien-3β-ol32138-69-5
417-iodoandrosta-5,16-dien-3β-acetate ester114611-53-9
Venetoclax & Intermediates
No.ProductCAS No.
15-hydroxy-7-azaindole98549-88-3
2methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate1235865-75-4
31-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine1228780-72-0
43-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide1228779-96-1
Lorlatinib & Intermediates
No.ProductCAS No.
1Lorlatinib1454846-35-5
21-methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile hydrochloride1643141-20-1
35'-fluoro-2'-iodoacetophenone914225-70-0
4(S)-1-(5-fluoro-2-iodophenyl)ethan-1-ol1454847-96-1
5methyl (R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate1454848-00-0
Brexpiprazole & Intermediates
No.ProductCAS No.
1Brexpiprazole913611-97-9
27-hydroxyquinolin-2(1H)-one70500-72-0
37-(4-chlorobutoxy)-4a,8a-dihydroquinolin-2(1H)-one913613-82-8
44-bromobenzo[b]thiophene5118-13-8
51-(benzo[b]thiophen-4-yl)piperazine hydrochloride913614-18-3
Diroximel Fumarate & Intermediates
No.ProductCAS No.
1Diroximel Fumarate1577222-14-0
21-(2-hydroxyethyl)pyrrolidine-2,5-dione18190-44-8
Vericiguat & Intermediates
No.ProductCAS No.
1Vericiguat1350653-20-1
25-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide1350653-27-8
32-(phenyldiazenyl)malononitrile6017-21-6
Eltrombopag & Intermediates
No.ProductCAS No.
1Eltrombopag496775-61-2
23'-amino-2'-hydroxybiphenyl-3-carboxylic acid376592-93-7
33,4-dimethylphenylhydrazine hydrochloride86746-50-1
Vibegron & Intermediates
No.ProductCAS No.
1Vibegron1190389-15-1
2tert-butyl (4-(3-(dimethoxyphosphoryl)-2-oxopropyl)phenyl)carbamate494224-44-1
3tert-butyl (4S,5R)-4-formyl-2,2-dimethyl-5-phenyloxazolidine-3-carboxylate163625-46-5
4(6S)-4,6,7,8-tetrahydro-4-oxo-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid1190392-22-3
5(R)-((2R,5S)-5-(4-aminobenzyl)pyrrolidin-2-yl)(phenyl)methanol1295539-30-8
6sodium (S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylate1421271-01-3
Fezolinetant & Intermediates
No.ProductCAS No.
1Fezolinetant1629229-37-3
2(R)-3-methylpiperazin-2-one922178-61-8
3(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one1383146-20-0
43-methyl-1,2,4-thiadiazole-5-carbohydrazide1375066-73-1
Vismodegib & Intermediates
No.ProductCAS No.
12-(2-chloro-5-nitrophenyl)pyridine879088-40-1
24-chloro-3-(pyridin-2-yl)aniline879088-41-2
Trametinib & Intermediates
No.ProductCAS No.
1Trametinib871700-17-3
2Trametinib DMSO solvate1187431-43-1
33-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione871700-22-0
4N-(3-(3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-ylamino)phenyl)acetamide871700-25-3
Elinzanetant & Intermediates
No.ProductCAS No.
1Elinzanetant929046-33-3
2pyrazino[2,1-c][1,4]oxazine, octahydro-7-[(phenylmethoxy)methyl]-, (7S,9aS)-, ethanedioate (1:2)1268364-46-0
3N-[6-chloro-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-N,a,a-trimethy825643-73-0
Dantrolene Sodium & Intermediates
No.ProductCAS No.
15-(4-nitrophenyl)-2-furaldehyde7147-77-5
21-aminohydantoin hydrochloride2827-56-7
Tovorafenib & Intermediates
No.ProductCAS No.
1ethyl 2-[1-[[(phenylmethoxy)carbonyl]amino]ethyl]-5-thiazolecarboxylate1095823-50-9
22-[1-[[(phenylmethoxy)carbonyl]amino]ethyl]-5-thiazolecarboxylic acid1095823-52-1
35-chloro-4-(trifluoromethyl)pyridin-2-amine1095823-39-4
Lazertinib & Intermediates
No.ProductCAS No.
1Lazertinib443797-96-4
2N1-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidin-2-yl)-6-methoxy-4-morpholinobenzene-1,3-diamine1903009-56-2
34-[4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl]-N-[2-methoxy-4-(4-morpholinyl)-5-nitrophenyl]-2-pyrimidinamine1903009-55-1
45-chloro-4-(trifluoromethyl)pyridin-2-amine1903010-39-8
51-(2-chloropyrimidin-4-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde1903010-38-7
Lemborexant & Intermediates
No.ProductCAS No.
1Lemborexant1369764-02-2
2(1S,5R)-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one528587-70-4
32,4-dimethyl-5-pyrimidinol412003-95-3
Daraxonrasib (RMC-6236) & Intermediates
No.ProductCAS No.
1methyl (S)-1-((S)-3-(4-bromothiazol-2-yl)-2-((1S,2S)-2-methylcyclopropane-1-carboxamido)propanoyl)hexahydropyridazine-3-carboxylate3060084-27-4
2(S)-1-((S)-3-(4-bromothiazol-2-yl)-2-((1S,2S)-2-methylcyclopropane-1-carboxamido)propanoyl)hexahydropyridazine-3-carboxylic acid3060084-22-9
35-[2-((1S)-1-methoxyethyl)pyridin-3-yl]-2,2-dimethyl-5-oxopentanoic acid2641451-48-9
4(S)-3-(5-bromo-2-(2-(1-methoxyethyl)pyridin-3-yl)-1H-indol-3-yl)-2,2-dimethylpropanoic acid2641451-49-0
5ethyl (S)-3-(5-bromo-2-(2-(1-methoxyethyl)pyridin-3-yl)-1H-indol-3-yl)-2,2-dimethylpropanoate2641451-50-3
63-[5-bromo-2-[2-[(1S)-1-methoxyethyl]pyridin-3-yl]-1H-indol-3-yl]-2,2-dimethylpropan-1-ol3082421-34-6
7(S)-3-(5-bromo-1-ethyl-2-(2-(1-methoxyethyl)pyridin-3-yl)-1H-indol-3-yl)-2,2-dimethylpropan-1-ol2641820-94-0
8(S)-3-(5-bromo-1-ethyl-2-(2-(1-methoxyethyl)pyridin-3-yl)-1H-indol-3-yl)-2,2-dimethylpropyl acetate2865127-17-7
9(S)-3-(5-bromo-1-ethyl-2-(2-(1-methoxyethyl)-5-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indol-3-yl)-2,2-dimethylpropan-1-ol3060115-68-3

Biological & Small Nucleic Acid Products

Biological raw materials and small nucleic acid products are one of the company's core R&D directions, covering the whole chain from research and development to industrialization.

Product list under preparation — please contact us for the latest catalogue.

Other Fine Chemicals

Fine chemicals for the cosmetics, nutraceutical and food industries, with OEM production services available.

Product list under preparation — please contact us for the latest catalogue.
Links: NMPA| CPHI China
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Add: No. 52 Zhaiying South Street, Shijiazhuang, Hebei, China  Tel/Fax: +86-311-6759 1193  E-mail: sales@dingminpharma.com  www.dingminpharma.com
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