Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd
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Model No.: CAS:1230487-00-9
Brand: DM
Grade Standard: Medicine Grade
Type: Organic Chemicals
State: Solid
Volatile: Not Volatile
Packaging: double PE with aluminium foil bag
Productivity: 100kg/month
Transportation: Ocean,Air
Place of Origin: Hebei,China
Supply Ability: 100kg/month
Certificate: ISO9001
Port: Shanghai
Payment Type: L/C,T/T,Paypal
Incoterm: FOB,CIF
Product name:BAF-312(SiponiMod)
CAS:1230487-00-9
| ITEMS | SPECIFICATION | RESULTS |
| Appearance | White to off-white powder | Conforms |
| Identification(RT by HPLC) | Conform with CRS | Conforms |
| Water (KF) | ≤2.0% | 1.63% |
| Heavy metals | ≤10ppm | <10ppm |
| Residue on ignition | ≤0.1% | 0.006% |
| Related substances | Any single known IMP≤0.10% | 0.03% |
|
| Any single unknown IMP≤0.50% | 0.07% |
|
| Total impurities≤1.00% | 0.27% |
| Assay(0.1N HCIO4) | 98.0 ~ 102.0%% | 99.8% |
| Storage | Sealed and stored at 2-8 °C in a dry place or at room temperature. | |
| Conclusion: Complies with Standard. | ||
Specification:98%
Siponimod, also known as BAF-312, is a a potent and orally selective S1P Receptor Modulator with EC50 value of 0.39nM for S1P1 receptors and 0.98nM for S1P5 receptors, respectively. Development of sphingosine-1-phosphate receptor 1 (S1P1) modulators to dampen inflammation and its sequelae is becoming increasingly promising for treating medical conditions characterized by significant immunopathology.
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