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Decitabine intermediate Pharmaceutical 5-Azacytosine CAS No 931-86-2:
Chemical Name: 5-Azacytosine
Molecular weight: 112.09
Appearance: crystalline solid
Cyproterone acetate has antagonistic properties towards the 5-Aza-2'-Deoxycytidine, has been reported to cause phosphorylation inhibition of 2'-deoxycytidine in certain cells and the incorporation of 2'-deoxycytidine into DNA. Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits Dnmt (DNA methyltransferase). DNA methylation has been noted to be important in determining apoptotic susceptibility to histone deacetylase inhibitors, and its prevention can cause gene silencing and transcriptional repression. Other studies suggest that cell exposure to 5-Aza-2'-Deoxycytidine causes a change in replication timing, reactivation of repressed genes, and decondensation of heterochromatin. Furthermore, this agent demonstrates the ability to induce histone hyperacetylation in murine centromeric heterochromatin and also affect intranuclear distribution of histone deacetylase 2.
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Decitabine intermediate 5-Azacytosine CAS No 931-86-2:
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Shijiazhuang Dingmin Pharmaceutical Sciences Co., Limited is a professional company ocusing on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. We have a R&D center and two plants in Shijiazhuang, Hebei Province. Our Products include active pharmaceutical ingredients (API), pharmaceutical and agrochemical intermediates and chiral compounds. We have won the trust of a wide range of customers/partners in the industry. Our major products are antineoplastic, cardiovascular and antibiotics and their intermediates.
In order to maintain continuous innovation and R & D capability, we maintain long-term and close cooperation with many research institutions and universities, Our co-production plants are located in Anhui, Jiangsu, Zhejiang and Inner Mongolia. The products have been sold to Europe, America, Southeast Asia and other countries and regions
Having upholding the " integrity, profession , innovation, win-win" as business philosophy, we believe that we are able to be stronger and stronger because of the excellent quality, favorable price and full-hearted service. We would like to sincerely welcome friends from all sectors to co-create a brilliant tomorrow together.
"The business upholds the philosophy of ""Be No.1 in high-quality, be rooted on credit and trustworthiness for growth"", will keep on to serve previous and new prospects from home and overseas whole-heatedly for Low price pharmaceutical 5-Azacytosine CAS No 931-86-2. The product will supply to all over the world, such as: Virgin Islands (U.S.),Syrian Arab Republic,Cyprus. we have 8 years experience of production and 5 years experience in trading with the customers all over the world. our clients mainly distributed in the North America Africa and Eastern Europe. we can supply high quality products with the very competitive price.
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