Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd
Model No.: DM 936563-96-1
Function: Specialist Drugs
Certification: FDA, SGS, GMP
Grade Standard: Medicine Grade
Type: Chemical Reagent
Volatile: Not Volatile
Appearence: White Powder
Packaging: As required
Ibrutinib is a small molecule BTK inhibitor that binds covalently to cysteine residues in the active site of BTK, thereby inhibiting its activity. BTK full name Bruton'styrosinekinase, transmits signals in the BCR signaling pathway and cytokine receptor signaling pathway, mediates B cell migration, chemotaxis, and adhesion. Preclinical studies have demonstrated that ibrutinib can inhibit the proliferation and survival of malignant B cells.Ibrutinib (PCI-32765) is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc.
Product name: ibrutinib, 2-Propen-1-one, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-
Cas Number: 936563-96-1
Moculer weight: 386.47
Molar mass: 440.497
Appearance: Off-white powder
Assay(By HPLC): ≥99.0%
Our productions of Inrutinib Intermediates:
Picture of Axitinib CAS NO 319460-85-0:
Package & Shipping:
1. Preferentially DHL or FedEx for quantity less than 50KG; Air shipping for 100KG above; Sea shipping for quantity over 500KG.
2. We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.
Delivery can be offered.
- Utilizing your own freight-forwarder
- FOB to a port in China
- CIF to a port near you
1. Supply high quality products with reasonable prices for pharmaceutical factory.
2. In time delivery, Packing pictures and loading video before loading.
3. Various documents(COA, MSDS, ROS, MOA etc.) and factory audit available.
4. Pre-sale consultation and post-sale service available.
5. Provide market informations to make customers fully informed.
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Limited is a professional company ocusing on the R&D, production, marketing and technical service of APIs and Pharmaceutical Intermediates. We have a R&D center and two plants in Shijiazhuang, Hebei Province. Our Products include Active Pharmaceutical Ingredients (API), pharmaceutical and Agrochemical Intermediates and chiral compounds. We have won the trust of a wide range of customers/partners in the industry. Our major products are antineoplastic, cardiovascular and antibiotics and their intermediates.
In order to maintain continuous innovation and R & D capability, we maintain long-term and close cooperation with many research institutions and universities, Our co-production plants are located in Anhui, Jiangsu, Zhejiang and Inner Mongolia. The products have been sold to Europe, America, Southeast Asia and other countries and regions
Having upholding the " integrity, profession , innovation, win-win" as business philosophy, we believe that we are able to be stronger and stronger because of the excellent quality, favorable price and full-hearted service. We would like to sincerely welcome friends from all sectors to co-create a brilliant tomorrow together.
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