Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

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Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd
HomeProductsOthersZZWXG-2021 Drug for treatment of idiopathic pulmonary fibrosis(IF) Pirfenidone 53179-13-8

ZZWXG-2021 Drug for treatment of idiopathic pulmonary fibrosis(IF) Pirfenidone 53179-13-8

  • $50
    ≥1
    Gram
Payment Type:
L/C,T/T,D/A,Paypal
Incoterm:
FOB,CIF
Min. Order:
1 Gram
Transportation:
Ocean,Air,Express
Port:
shanghai,hangzhou
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  • Product Description
Overview
Product Attributes

Model No.53179-13-8

BrandDM

Supply Ability & Additional Information

Packagingas per request

Productivity100kgs/month

TransportationOcean,Air,Express

Place of OriginHebei,China

Supply Ability100kgs/month

CertificateISO9001

Portshanghai,hangzhou

Payment TypeL/C,T/T,D/A,Paypal

IncotermFOB,CIF

Packaging & Delivery
Selling Units:
Gram
Package Type:
as per request
Picture Example:

Product Name pirfenidone
CAS 53179-13-8
Appearance White Powder
Shelf life 2 years
Purity 99%min
Usage  Pharmaceuticals



Pirfenidone is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF). IPF causes scar tissue to form deep within your lungs. The scar tissue thickens and becomes stiff or thick over time, which can make it harder for your lungs to work. Decreased lung function can make it hard for you to breathe. Other medical problems can occur when your brain, heart, and other organs do not get enough oxygen.

 The cause of IPF is often unknown, but this condition is a progressive disease that can be fatal. Pirfenidone is not a cure for IPF, but this medicine may slow the progress of this disease.

 

 In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.

 

We are the professional manufacturer of API,Raw Material Pharma,Pharmaceutical Intermediates,Active Pharmaceutical Ingredients ,Agrochemical Intermediates and  Fine Chemicals.with best quality and competitive price.




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