Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

sales@dingminpharma.com

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Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

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Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

 [Hebei,China]

Business Type:Manufacturer , Trade Company , Distributor/Wholesaler

Main Markets: Americas , Asia , East Europe , Europe , North Europe , Oceania , Other Markets , West Europe , Worldwide , Africa , Caribbean , Middle East

Exporter:81% - 90%

Certs:ISO9001, CCC, FDA, MSDS, FCC, REACH, RoHS

Description:Decitabine Intermediate 931-86-2,5-Azacytosine CAS No. 931-86-2,CAS No. 931-86-2 -Azacytosine

HomeProductsAPIs And IntermediatesDecitabine IntermediatesLow price pharmaceutical 5-Azacytosine CAS No. 931-86-2
Low price pharmaceutical 5-Azacytosine CAS No. 931-86-2
  • Low price pharmaceutical 5-Azacytosine CAS No. 931-86-2

Low price pharmaceutical 5-Azacytosine CAS No. 931-86-2

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Overview
Product Attributes

Model No.: DM 931-86-2

Purity: 99%

Appearence: White Powder

Supply Ability & Additional Information

Packaging: 25KG/Drum or as required

Productivity: BULK STOCK

Transportation: Ocean,Air

Place of Origin: HEBEI,CHINA

Certificate: ISO9001

Port: Shanghai,Shenzhen,Qingdao

Payment Type: L/C,T/T,D/P

Incoterm: FOB,CIF

Packaging & Delivery
Selling Units:
Kilogram
Package Type:
25KG/Drum or as required

Decitabine intermediate Pharmaceutical 5-Azacytosine CAS No 931-86-2:

Chemical Name: 5-Azacytosine
CAS No.:931-86-2

Molecular Formula:C3H4N4O

Molecular weight: 112.09

Appearance: crystalline solid


Cyproterone acetate has antagonistic properties towards the 5-Aza-2'-Deoxycytidine, has been reported to cause phosphorylation inhibition of 2'-deoxycytidine in certain cells and the incorporation of 2'-deoxycytidine into DNA. Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits Dnmt (DNA methyltransferase). DNA methylation has been noted to be important in determining apoptotic susceptibility to histone deacetylase inhibitors, and its prevention can cause gene silencing and transcriptional repression. Other studies suggest that cell exposure to 5-Aza-2'-Deoxycytidine causes a change in replication timing, reactivation of repressed genes, and decondensation of heterochromatin. Furthermore, this agent demonstrates the ability to induce histone hyperacetylation in murine centromeric heterochromatin and also affect intranuclear distribution of histone deacetylase 2.



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