Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd
sales@dingminpharma.com
86-311-67591193
Model No.: DM 1152311-62-0
Packaging: As required
Productivity: Stock Available
Transportation: Ocean,Air,Courier
Place of Origin: Hebei,China
Supply Ability: As per order
Certificate: ISO9001
Port: Shanghai,Shenzhen,Hangzhou
Payment Type: L/C,T/T,D/P
Incoterm: FOB,CIF,CIP
Strong Products Tezacaftor (VX-661) CAS: 1152311-62-0 99%+
Product Name: 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide
Cas No.: 1152311-62-0
Appearance:White Powder
Purity:99%+
Package&Shipping:
Package:Double PE Bag with Foil Bag or As required
Delivery time:Stock available
Port:Any port in China
VX-661 is an investigational compound that promotes the maturation of delta F508 mutants of the cystic fibrosis transmembrane conductance regulator (CFTR). Delta F508 CFTR represents a class of CFTR mutation that is characterized by impaired processing of misfolded CFTR proteins and reduced accumulation of the protein at the cell surface. VX-661 is intended to facilitate trafficking of CFTR to the epithelial cell membrane. It may be combined with the CFTR potentiator ivacaftor (Item No. 15145) to stimulate both CFTR accumulation and opening at the apical epithelial surface.
Our productions of Lumacaftor (VX-809) Intermediates:
Tezacaftor (VX-661) 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl] -cyclopropanecarboxamide 1152311-62-0 2-bromo-5-fluoro-4-nitroaniline 952664-69-6 (((2,2-dimethylbut-3-yn-1-yl)oxy)methyl)benzene 1092536-54-3 (R)-2-((benzyloxy)methyl)oxirane 14618-80-5 (R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol 4-methylbenzenesulfonate 1294504-64-5 (R)-1-(5-amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol 1294504-67-8 2-(4-(benzyloxy)-3,3-dimethylbut-1-yn-1-yl)-5-fluoro-4-nitroaniline / 2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-5-nitro-1H-indole 1638771-94-4
Other Project releated
Ivacaftor (VX-770) N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide CAS: 873054-44-5 Lumacaftor (VX-809) 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-3-methylpyridin-2-yl) CAS:936727-05-8
Product Categories : APIs And Intermediates > Caftor Series Intermediates
Privacy statement: Your privacy is very important to Us. Our company promises not to disclose your personal information to any external company with out your explicit permission.
Fill in more information so that we can get in touch with you faster
Privacy statement: Your privacy is very important to Us. Our company promises not to disclose your personal information to any external company with out your explicit permission.
Contact Now